Peptide Hexarelin Acetate Bulking Cycle Steroids for Hormone Anabolic Steroids

Peptide Hexarelin Acetate for Hormone Anabolic Steroids 2mg/Vials 140703-51-1

Hexarelin Acetate

Sequence: His-D-2-methyl-Trp-Ala-Trp-D-Phe-Lys-NH2
Molecular formula: C47H58N12O6
MW : 887.04022
CAS number: 140703-51-1
PubChem: CID 5464109
Synonyms: Hexarelin Acetate, HEX, Examorelin
Appearance : White Powder
Purity : 99%
Grade : Pharmaceutical Grade
Storage: Closed, below 2 ~ 8ºC preservation
Usage : A synthetic can promote GH release six peptide, clinically used in the treatment of growth hormone secretion deficiency.

Specifications :

Description:

secretagogue receptor is a G protein-coupled receptor that binds ghrelin and plays a role in energy homeostasis and regulation of body weight.

The potential clinical usefulness of these GH releasing hexapeptides is also reinforced by observations that long-term administration produces elevations in circulating concentrations. Long term treatment with GHRP-6 similarly has been shown to elevate serum as well asbinding protein-3 concentrations and promote linear growth.

Application:

Ghrelin is an appetite-regulating factor secreted from peripheral organs that is involved in regulation of energy homoeostasis via binding to the receptor resulting in the secretion of by the pituitary gland. The pathway activated by binding of ghrelin to the secretagogue receptor, GHSR1a, regulates the activation of the downstream mitogen-activated protein kinase, Akt, nitric oxide synthase, and AMPK cascades in different cellular systems.

One of the important features of GHSR1a displays constitutive activity possessing basal activity in the absence of an agonist, resulting in a high degree of receptor internalization as well as of signaling activity.Inverse agonists for the ghrelin receptor could be particularly interesting for the treatment of obesity.This activity seems to provide a tonic signal required for the development of normal height, probably through an effect on the GH axis.
Description:

Growth hormone secretagogue receptor is a G protein-coupled receptor that binds ghrelin and plays a role in energy homeostasis and regulation of body weight.

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